Clinical aspect and factors affecting outcome of meningococcal infection in Makkah

This study included 125 cases with meningococcal infection The majority of cases were due to group A meningococci [88.8%], most of them admitted in Ramaddan time of Umra in Makka. High incidence of the disease developed in the age group 24-60 years and the males were affected more than females. Fever, headache, vomiting, disturbed level of consciousness and neck stiffness were the predominant symptoms and signs. The mortality rate was relatively high [20.8%]. A significant relationship was found between the death and extensive rashes, leucopenia, normal WBCs count, shock and disturbed level of consciousness grade II, IV, but no significant relationship between the death and C. S. F pleocytosis, petechiae, peripheral leucocytosis and stage I and disturbed level of consciousness

situation of nosocomial infection from patients with congo/crimean hemorrhagic fever in Makkah

From 20 May 1990 to 12 December 1992, 28 patients with Congo-Crimean hemorrhagic fever were admitted in King Faisal Hospital, Makkah. All the patients were evaluated clinically and laboratory and finally diagnosed by the using antibody titer. 15 hospital staff [in close contact with the patients were screened for the clinical manifestations laboratory results and the antibody titer to Congo- Crimean hemorrhagic fever. The results revealed that the secondary case of the disease in Makkah was unusual and the air borne route does not play any role in the transmission of the disease

Prevalence of hepatitis E among patients with acute hepatitis

This study included 361 patients who were admitted with clinical manifestations and laboratory results of acute virus hepatitis. It was carried out in King Faisal Hospital, Makkah, the only center for infectious disease there. The results revealed that the hepatitis A is the most common cause of acute hepatitis [74.5%], and the male were affected more than females [56.5%, 43.5%]. Both acute hepatitis and hepatitis E have high prevalence rate below the age of 12 years. Hepatitis E virus plays a minor role [11.3%] as a cause of acute hepatitis in Makkah and most of the cases were coming from low standard area where poor sanitary disposal of excreta. So, improvement in water supplies, sewage disposal and hygiene should be effective in lowering HEV incidence